Welcome to the Anantharam Lab! We investigate the mechanisms underlying the fundamental cellular process of calcium-triggered exocytosis. Exocytosis controls the release of neurotransmitters in the brain and hormones from endocrine cells in the periphery. Our studies of exocytosis are rooted in important physiological contexts relevant to the sympathetic stress response and whole-body energy metabolism. Our work employs high resolution optical methods (TIRF, confocal, and multi-photon microscopy), in conjunction with in situ electrophysiology and synthetic biology.
